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Quit-Smoking Medicines and Nicotine Replacement Therapy: What Works

Quit-Smoking Medicines and Nicotine Replacement Therapy: What Works

Quit-smoking medicines can reduce cravings and withdrawal symptoms and improve the chance of stopping cigarettes successfully. They work best when combined with behavioral support.

Nicotine replacement therapy (NRT)

NRT provides nicotine without the toxic products of burning tobacco. Common forms include:

  • Nicotine patch
  • Nicotine gum
  • Nicotine lozenge
  • Nicotine inhaler
  • Nicotine nasal spray

Patch plus gum or lozenge

The old advice that people using a nicotine patch cannot also use nicotine gum is incorrect. A long-acting patch plus a short-acting product such as gum or lozenge can improve quit success compared with using one form of NRT alone.

Prescription medicines

Varenicline and bupropion SR are non-nicotine prescription medicines used for smoking cessation. Which option is appropriate depends on medical history, other medicines, pregnancy status, previous quit attempts and personal preference.

Use products correctly

NRT dose and technique matter. Nicotine gum, for example, is generally chewed briefly and then “parked” between the cheek and gum rather than chewed continuously like ordinary gum. Follow product directions or ask a pharmacist or clinician for help.

Do not use lung-detox supplements as a substitute

Commercial “lung cleanse,” detox and herbal smoking-cessation products are not substitutes for proven cessation treatment.

Pregnancy and special situations

Smoking cessation is especially important during pregnancy, but medication decisions should be individualized with a healthcare professional. People with significant medical conditions or complex medication regimens should also seek advice before starting prescription treatment.

Related guides

Editorial sources

This article provides general education and does not replace medical or pharmacist advice about medication choice or dosing.

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